PUBLICATIONS

DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.

Wielscher, M., Mandaviya, P.R., Kuehnel, B. et al. Nat Commun 13, 2408 (2022)

Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases.

Yong Li, Luca Rampoldi, Anna Köttgen. JCI Insight (2022)

Genome-wide meta-analysis of phytosterols reveals five novel loci and

a detrimental effect on coronary atherosclerosis.

Scholz, M., Horn, K., Pott, J. et al. Nat Commun 13, 143 (2022)

 

Reproductive history and blood cell DNA methylation later in life: the Young Finns Study.

Harville, E.W., Mishra, P.P., Kähönen, M. et al. Clin Epigenet 13, 227 (2021) 

Assessment of plasma ceramides as predictor for subclinical atherosclerosis.

Pashupati P. Mishra, Binisha H. Mishra, Leo-Pekka Lyytikäinen, Mika Hilvo, Markus Juonala, Mika Kähönen, Nina Hutri-Kähönen, Dimitrios I. Fotiadis, Olli T. Raitakari, Reijo Laaksonen, Terho Lehtimäki,  Atherosclerosis Plus, Volume 45, Pages 25-31 (2021)

Genomics-based identification of a potential causal role for acylcarnitine metabolism in depression.

Yuri Milaneschi, Matthias Arnold, Gabi Kastenmüller, Siamak Mahmoudian Dehkordi, Ranga R. Krishnan, Boadie W. Dunlop, A. John Rush, Brenda W. J. H. Penninx, Rima Kaddurah-Daouk, for the Mood Disorders Precision Medicine Consortium (MDPMC). medRxiv 2021.10.18.21265157 (2021)

Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait loci,

Jaakko Laaksonen, Pashupati P Mishra, Ilkka Seppälä, Emma Raitoharju, Saara Marttila, Nina Mononen, Leo-Pekka Lyytikäinen, Marcus E Kleber, Graciela E Delgado, Maija Lepistö, Henrikki Almusa, Pekka Ellonen, Stefan Lorkowski, Winfried März, Nina Hutri-Kähönen, Olli Raitakari, Mika Kähönen, Jukka T Salonen, Terho Lehtimäki, Human Molecular Genetics (2021)

Uncovering the shared lipidomic markers of subclinical osteoporosis-atherosclerosis comorbidity: The Young Finns Study, Binisha H. Mishra, Pashupati P. Mishra, Nina Mononen, Mika Hilvo, Harri Sievänen, Markus Juonala, Marika Laaksonen, Nina Hutri-Kähönen, Jorma Viikari, Mika Kähönen, Olli T. Raitakari, Reijo Laaksonen, Terho Lehtimäki, Bone, Volume 151,116030 (2021)

 

Association between Oral Pathology, Carotid Stenosis, and Oral Bacterial DNA in Cerebral Thrombi of Patients with Stroke, Olli Patrakka, Helena Mehtonen, Sari Tuomisto, Juha-Pekka Pienimäki, Jyrki Ollikainen, Heini Huhtala, Tanja Pessi, Niku Oksala, Terho Lehtimäki,

Jorma Järnstedt, Mika Martiskainen, Pekka J. Karhunen, Stroke Research and Treatment, vol. 2021 (2021)

 

Genetic differential susceptibility to the parent–child relationship quality and the life span development of compassion. Henrik Dobewall, Liisa Keltikangas-Järvinen, Aino Saarinen, Leo-Pekka Lyytikäinen, Igor Zwir, Robert Cloninger, Olli T. Raitakari,

Terho Lehtimäki, Mirka Hintsanen,  Developmental Psychobiology, 63, e22184 (2021)

C-reactive protein and temperament: An instrumental variable analysis,

Ari Clemens, Pashupati P. Mishra, Eirini Flouri, Terho Lehtimäki, Olli Raitakari, Liisa Keltikangas-Järvinen, Katriina Heikkilä,

Brain, Behavior, & Immunity - Health, Volume 14 (2021)

Methylation status of nc886 epiallele reflects periconceptional conditions and is associated

with glucose metabolism through nc886 RNAs.

Marttila, S., Viiri, L.E., Mishra, P.P. et al. Clin Epigenet 13, 143 (2021)

 

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.

McCartney, D.L., Min, J.L., Richmond, R.C. et al. Genome Biol 22, 194 (2021)

Meta-analysis of epigenome-wide association studies of carotid intima-media thickness.

Portilla-Fernández, E., Hwang, SJ., Wilson, R. et al. Eur J Epidemiol 36, 1143–1155 (2021)

 

Prehospital Adenosine Diphosphate Receptor Blocker Use, Culprit Artery Flow, and Mortality in STEMI: The MADDEC Study. Hautamäki M, Lyytikäinen LP, Eskola M, et al. Clin Drug Investig. 41(7):605-613 (2021)

 

Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health.

Marttila, S., Rovio, S., Mishra, P.P. et al. Sci Rep 11, 9203 (2021)

 

Modular genome-wide gene expression architecture shared by early traits

of osteoporosis and atherosclerosis in the Young Finns

Study. Mishra, B.H., Mishra, P.P., Raitoharju, E. et al. Sci Rep 11, 7111 (2021)

The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.

Kalaoja, M., Corbin, L.J., Tan, V.Y., Ahola-Olli, A.V., Havulinna, A.S., Santalahti, K., Pitkänen, N., Lehtimäki, T., Lyytikäinen, L.-P., Raitoharju, E., Seppälä, I., Kähönen, M., Ripatti, S., Palotie, A., Perola, M., Viikari, J.S., Jalkanen, S., Maksimow, M., Salomaa, V., Salmi, M., Raitakari,

O.T., Kettunen, J. and Timpson, N.J. Obesity, 29: 428-437 (2021)

Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts.

Laaksonen, J., Mishra, P.P., Seppälä, I. et al. Sci Rep 11, 611 (2021)

 

The prognostic significance of T-wave inversion according to ECG lead group

during long-term follow-up in the general population.

Istolahti, T, Lyytikäinen, L-P, Huhtala, H, et al. Ann Noninvasive Electrocardiol. 26:e12799 (2021)

 

DNA methylation signatures of aggression and closely related constructs:

A meta-analysis of epigenome-wide studies across the lifespan.

van Dongen, J., Hagenbeek, F.A., Suderman, M. et al. Mol Psychiatry 26, 2148–2162 (2021)

 

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.

Gorski, MathiasAlizadeh, Behrooz Z.Abecasis, Goncalo et al., Kidney International, Volume 99, Issue 4, 926 - 939 (2020)

Epigenome-450K-wide methylation signatures of active cigarette smoking: The Young Finns Study.

Pashupati P. Mishra, Ismo Hänninen, Emma Raitoharju, Saara Marttila, Binisha H. Mishra, Nina Mononen, Mika Kähönen, Mikko Hurme, Olli Raitakari, Petri Törönen, Liisa Holm, Terho Lehtimäki; Biosci Rep; 40 (7): BSR20200596 (2020)

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